A large pedicle on examination is most commonly associated with which condition?

A large pedicle, when examined in the context of congenital heart conditions, is most commonly associated with transposition of the great arteries (TGA). In TGA, the anatomical arrangement of the aorta and pulmonary artery leads to distinct hemodynamic changes that can result in prominent pulmonary vascular markings and vascular pedicles on imaging, particularly on chest X-rays.

In TGA, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle, creating separate circulatory pathways for oxygenated and deoxygenated blood. This arrangement can be visualized as a large pedicle on radiological exams, due to the way the vessels position themselves and their associated vascular supply.

Conditions like truncus arteriosus, tetralogy of Fallot, and coarctation of the aorta present different hemodynamic profiles and imaging characteristics. Truncus arteriosus involves a single vessel giving rise to both the aorta and the pulmonary arteries, therefore typically does not present with a large pedicle in the same manner. Tetralogy of Fallot involves a combination of defects that often leads to right ventricular outflow obstruction but does not induce the same prominent vascular structures as seen in TGA. Coar