What condition is characterized by white papules over the face, limbs, and trunk of a newborn, along with eosinophils?

The condition characterized by white papules over the face, limbs, and trunk of a newborn, coupled with the presence of eosinophils, is indicative of erythema toxicum. This common benign dermatosis typically appears within the first few days after birth and is distinguished by its distinctive lesion formation, which includes erythematous macules and papules, often with a central vesicle or pustule.

The presence of eosinophils in the lesions is a key feature that helps differentiate erythema toxicum from other neonatal skin conditions. Eosinophils are a type of white blood cell involved in inflammatory responses, often associated with allergic reactions and parasitic infections, but in this case, their presence indicates the body's normal inflammatory response to the skin lesions.

Erythema toxicum is generally self-limiting, requiring no specific treatment, and typically resolves within the first few weeks of life. The appearance of these lesions is common and generally does not indicate any underlying pathological condition, making it an important aspect of neonatal skin assessment.