What congenital condition is characterized by a cicatricial skin rash and limb hypoplasia?

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The correct answer pertains to a congenital condition characterized by a cicatricial skin rash and limb hypoplasia. This presentation aligns with the effects of a specific congenital infection known as congenital varicella syndrome, which is part of the group of conditions associated with TORCH infections (Toxoplasmosis, Other, Rubella, Cytomegalovirus, and Herpes simplex virus).

Congenital varicella syndrome can lead to various anomalies, including skin scarring (cicatricial rash) and limb deformities or hypoplasia due to the teratogenic effects of the varicella-zoster virus when infection occurs during pregnancy. The presence of a skin rash and abnormalities in limb development clearly indicates a developmental disruption that aligns with this viral infection.

In contrast, the other conditions listed do not typically present with these specific symptoms. Meckel's diverticulum is an abnormality of the intestine. Cystic fibrosis is primarily a respiratory and gastrointestinal disorder, and Hirschsprung's disease affects the colon and is not associated with skin or limb anomalies. Therefore, the distinctive symptoms provided in the question correlate directly with the effects of a TORCH infection, making it the most accurate choice.

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