What is the main characteristic of a slapped cheek rash?

The main characteristic of a slapped cheek rash, which is commonly associated with fifth disease caused by parvovirus B19, is its sudden appearance, often following a mild fever. Typically, this rash manifests as bright red cheeks, giving the appearance of having been slapped, and it often occurs in children. The eruption can happen several days after the initial fever, which is part of the reason it is recognized as a distinct stage of the illness.

In contrast to the other options, the rash is not particularly itchy; rather, it can evolve into a more lacy pattern on the body or limbs, but it does not fade within a few hours. As the name and presentation imply, slapped cheek rash is a hallmark of a viral exanthema that can occur without notable respiratory symptoms, distinguishing it from other viral illnesses that typically present with such signs.