What thyroid condition can lead to pathological jaundice on day 14?

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Hypothyroidism can lead to pathological jaundice in newborns, particularly when it is congenital hypothyroidism. In the context of neonatal jaundice, hypothyroidism can disrupt the normal metabolism of bilirubin, contributing to its accumulation and resulting in increased bilirubin levels in the blood. This condition may manifest later, around day 14 of life, when the infant's physiological ability to manage bilirubin is challenged by the underlying thyroid dysfunction.

In cases of congenital hypothyroidism, there is a lack of thyroid hormones, which impairs various metabolic processes, including the conjugation and excretion of bilirubin. As bilirubin builds up in the blood, it leads to jaundice, which is deemed pathological if it persists well beyond the usual physiological jaundice that occurs in most neonates.

Other thyroid conditions, such as hyperthyroidism, typically do not lead to jaundice, and thyroiditis primarily refers to inflammation of the thyroid without the associated metabolic consequences that would typically influence bilirubin levels in this manner. Hence, while other options may refer to thyroid-related disorders, they aren't directly linked to causing pathological jaundice the way hypothyroidism is.

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