Which polio vaccine is considered safe for immunocompromised patients?

The Inactivated Polio Vaccine (IPV) is considered the safest option for immunocompromised patients because it contains killed virus and does not pose a risk of vaccine-derived poliovirus. IPV is administered via injection and induces an immune response without the risk of live virus replication. This characteristic makes it appropriate for individuals with weakened immune systems, such as those undergoing chemotherapy or living with certain genetic disorders.

In contrast, the Oral Polio Vaccine (OPV), which contains live attenuated virus, can lead to vaccine-derived poliovirus in immunocompromised individuals, posing a risk of paralysis. The Recombination Vaccine refers to a modified approach that may include technology not standard to the traditional vaccines, and the Live Attenuated Vaccine specifically, like OPV, includes live viruses that can be unsafe for those with compromised immunity. Thus, IPV remains the recommended choice for immunocompromised individuals, ensuring their protection against polio without additional health risks.