Which type of urine odor is considered a sign of metabolic disorder in infants?

A mousy odor in urine is particularly associated with a specific metabolic disorder known as phenylketonuria (PKU). This condition arises from the body's inability to break down phenylalanine, an amino acid found in many protein-containing foods. When this amino acid accumulates, it can lead to various neurological issues and is characterized by the distinctive mousy or musty smell of the urine.

The presence of this odor serves as an important clinical clue for medical professionals in the early diagnosis of PKU, particularly in infants. Early detection and intervention, including dietary modifications to limit phenylalanine intake, are crucial in preventing the developmental consequences associated with the disorder.

In contrast, the other odors associated with urine may indicate different conditions but are not specific to metabolic disorders. For example, sweet-smelling urine is often linked to the presence of glucose, as seen in uncontrolled diabetes, while ammonia odor could suggest a concentration of urea due to dehydration or urinary tract infections. Foul odor might be indicative of infections or other issues but does not specifically identify a metabolic disorder. Thus, the mousy odor stands out as a significant sign of a metabolic condition, particularly in infants.