Which vaccine is classified as a recombinant vaccine?

The hepatitis B vaccine is classified as a recombinant vaccine because it is produced through recombinant DNA technology. In this process, a gene that encodes a specific protein from the hepatitis B virus is inserted into yeast or other cells, which then produce the viral protein. This protein is harvested and purified, and it serves as the active ingredient in the vaccine. When administered, it stimulates the immune system to recognize the hepatitis B virus and mount a defense against it, leading to immunity without exposing the individual to the actual virus.

Recombinant vaccines are particularly advantageous because they are safe and can elicit a strong immune response while avoiding the risks associated with using live or inactivated pathogens. This technology has revolutionized vaccine development, promoting the production of effective vaccines using genetic engineering methods.

Other vaccines listed, such as diphtheria and measles vaccines, are typically inactivated or live attenuated, while the HPV vaccine, although it can have components that are recombinant, is a combination of recombinant techniques and viral-like particles. The unique aspect of the hepatitis B vaccine as a purely recombinant product distinguishes it clearly in this context.