Which vaccine is mentioned as causing hypotensive hyporesponsiveness?

The DPT vaccine, which stands for Diphtheria, Pertussis, and Tetanus, has been associated with a phenomenon known as hypotensive hyporesponsiveness. This condition can occur in children following the administration of the vaccine and is characterized by a sudden drop in blood pressure, which can lead to decreased responsiveness or lethargy.

This adverse reaction is linked to the whole-cell pertussis component of the DPT vaccine. Although such reactions are rare, understanding them is crucial in pediatrics, especially when discussing vaccine safety with parents and caregivers. The occurrence of hypotensive hyporesponsiveness is an important consideration in the management of vaccination programs and may affect recommendations or practices related to the administration of the DPT vaccine.

While other vaccines mentioned, such as the diphtheria and tetanus vaccines, are components of the DPT, they do not have the same association with hypotensive hyporesponsiveness when given alone. The measles vaccine is also not linked to this particular adverse event. This distinction is critical in recognizing the specific risks associated with the combination vaccine versus individual components.